News: Biomolecular Engineering

Creating new tools that harness light to probe the mysteries of cellular behavior, Princeton researchers have made discoveries about the formation of cellular components called membraneless organelles and the key role these organelles play in cells.
For bacteria facing a dose of antibiotics, timing might be the key to evading destruction. In a series of experiments, Princeton researchers found that cells that repaired DNA damaged by antibiotics before resuming growth had a much better chance of surviving treatment.
Most people can name at least a few bones of the human body, but not many know about the cytoskeleton within our cells, let alone the “microtubules” that give it its shape. Now, a group of Princeton researchers has resolved a long-standing controversy by identifying exactly how the body creates these micron-sized filaments.

Scientists have recently learned how to use light to control specific groups of neurons to better understand the operation of the brain, a development that has transformed areas of neuroscience.

For more than a century, biologists ignored a fundamental question about how cells do the business of sorting molecules in a crowd. Then came Cliff Brangwynne, whose surprising work showed that certain proteins separate into globules much like droplets of vinegar suspended in oil.